Stanford University is looking for Latino and non-Latino Caucasian volunteers 18 years or older with chronic hepatitis C (genotype 1) who have never received prior antiviral treatment for hepatitis C infection (e.g., interferon, ribavirin). This study will compare the effectiveness of Pegasys ® plus Copegus®. The study provides free study-related physical exams, medications and diagnostic tests. Pegasys® is administered by self-injection. Two liver biopsies are required. Ability to come to Stanford area for multiple, regular visits is also required. Subjects must meet study criteria in order to participate. Volunteers with chronic hepatitis C who are interested in participation in this study directed by Gabriel Garcia, MD, should contact the Liver Research Office @ (650) 724-7057.